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D. K. Zabolotny Institute of Microbiology and Virology
Institute for Problems of Cryobiology and Cryomedicine
Institute of Cell Biology
Institute of Molecular Biology and Genetics
O. O. Bohomolets Institute of Physiology
O. V. Palladin Institute of Biochemistry
R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology
Institute for Problems of Cryobiology and Cryomedicine 
 
23 Pereyaslavska St., 61015, Kharkiv, Ukraine
Phone: (057) 373 4143, 373 8807; fax: (057) 373 3084
e-mail:cryo@online.kharkov.ua
http://www.cryo.org.ua
 Director
Valentin I. Grischenko,
NAS academician

Established on February 11, 1972.

Main research lines:

- investigations into mechanisms of cryoinjury, cryoprotection, natural cold telerance of biological objects and their reparation after exposure to cold;

- finding effective methods for artificial cryoprotection of biological systems of various organization levels; developing relevant technologies for cryoconservation of biological objects and technical equipment for their implementation;

- using hypothermia, cryotherapy and cryopreserved biological objects to treat various types of diseases

- cell and tissue transplantation.

Science schools functioning at the Institute:

1. cryobiology and cryomedicine of reproductive system, cell and tissue therapy;

2. cryobiochemystry of membrane structures and cell cytoskeleton;

3. immunobiological problems in low-temperature preservation and use of biological objects;

4. low-temperature biophysics, cryoprotectors;

5. experimental cryomedicine, neurophysiology.

The Institute has the following research achievements of the international level:

- The structural hypothesis of cryodamage has been validated.

- A technology for human in vitro fertilization and gene pool preservation has been developed.

- The concept concerning the role of blood-brain barrier in the mechanisms of human and animal adaptation to low temperatures has been substantiated.

- A low-temperature bank of biological objects has been created, which has been awarded the status of the National Asset.

- A technology has been developed to produce biologically active cells from foetoplacental cells.

Novel technologies ready for implementation:

- a technology for cryopreserving sperm and embryos of fish, birds, mammals; programmable-freezing equipment for its implementation;

- a technology of extreme cryotherapy and hypothermia to treat various diseases;

- pre-sowing treatment of seeds;

- a technology for production, low-temperature preservation and use of immunobiological preparations obtained from human and animal foetoplacental system;

- trouble-free technologies for low-temperature storage and use of blood cells.

   
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